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PubMed Central Background Allostery is one of the most powerful and common ways of regulation of protein activity. However, for most allosteric proteins identified to date the mechanistic details of allosteric modulation are not yet well understood. Uncovering common mechanistic patterns underlying allostery would allow not only a better academic understanding Adult dating in milledgeville ohio the phenomena, but it would also streamline the de of novel therapeutic solutions.

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